When it comes to women’s sexual health, conversations often revolve around hormones, libido, and overall well-being, yet many women are unaware that there are FDA-approved medications specifically designed to address low sexual desire. If you’ve ever felt like your libido isn’t what it used to be and wondered if there’s a solution, you’re not alone.
At Vitality, we prioritize personalized, evidence-based care—including solutions for female sexual dysfunction. Two FDA-approved medications, Addyi (flibanserin) and Vyleesi (bremelanotide), offer options for women struggling with hypoactive sexual desire disorder (HSDD). Let’s break down what they are, how they work, and whether they may be right for you.
What Is HSDD?
Hypoactive Sexual Desire Disorder (HSDD) is a medical condition characterized by a persistent lack of sexual desire that causes distress. It’s important to distinguish HSDD from temporary dips in libido due to stress, relationship issues, or hormonal changes—HSDD is ongoing and unrelated to external factors.
HSDD can impact a woman’s confidence, relationships, and overall well-being, yet it’s often underdiagnosed because many women feel uncomfortable discussing it with their healthcare providers. The good news? There are medical treatments available.
Addyi (Flibanserin): The "Female Viagra"—Or Is It?
Often mistakenly called “female Viagra,” Addyi works very differently from the well-known blue pill for men. Unlike Viagra, which increases blood flow to the genitals, Addyi is a daily, non-hormonal pill that works in the brain to restore sexual desire in premenopausal women.
How It Works:
Addyi modulates serotonin and dopamine levels in the brain, helping to rebalance neurotransmitters involved in sexual desire.
It must be taken every night to be effective—this is not an "on-demand" medication like Viagra.
Clinical studies show that women taking Addyi reported an increase in sexual desire and a decrease in distress related to low libido.
Who Is It For?
Premenopausal women experiencing distress due to low sexual desire.
Those who have tried lifestyle changes (such as stress management, relationship counseling, and hormone therapy if needed) without success.
Potential Side Effects:
The most common side effects are dizziness, nausea, fatigue, and low blood pressure.
It cannot be taken with alcohol due to an increased risk of severe drops in blood pressure.
Vyleesi (Bremelanotide): The “On-Demand” Option
Unlike Addyi, Vyleesi is an injectable medication used as needed rather than a daily pill. It’s a self-administered subcutaneous injection (like an insulin shot) taken about 45 minutes before sexual activity.
How It Works:
Vyleesi activates melanocortin receptors in the brain, enhancing sexual desire in premenopausal women.
It does not need to be taken daily—just when needed.
Who Is It For?
Premenopausal women with HSDD who prefer an "as-needed" approach rather than a daily medication.
Women who cannot or do not want to take Addyi.
Potential Side Effects:
Nausea is the most common side effect (occurring in up to 40% of users). However, it is usually limited to the first dose, and most patients tolerate it well thereafter.
Temporary increase in blood pressure (not recommended for those with uncontrolled hypertension).
Some women experience flushing or headache after injection.
Which One Is Right for You?
Both medications are effective, but choosing between Addyi and Vyleesi depends on your lifestyle, preferences, and medical history.
Choose Addyi if:
You prefer a daily medication that gradually restores libido.
You do not drink alcohol regularly (due to interaction risks).
Choose Vyleesi if:
You want an on-demand option rather than a daily commitment.
You don’t mind an occasional injection before intimacy.
Both options require a prescription and medical evaluation to determine whether they’re safe for you.
Beyond Medications: A Holistic Approach to Sexual Wellness
While Addyi and Vyleesi are exciting advancements in women’s sexual health, they are just one piece of the puzzle. Addressing low libido often requires a comprehensive, multidisciplinary approach, which may include:
Hormone Optimization: Balancing testosterone, estrogen, and progesterone can play a critical role in sexual health.
Lifestyle Adjustments: Quality sleep, exercise, and stress reduction improve libido naturally.
Nutrition & Supplements: Certain nutrients and adaptogens (such as ashwagandha) may support sexual function.
Pelvic Floor Therapy: A healthy pelvic floor enhances sexual pleasure by improving blood flow, sensitivity, and muscle control, leading to stronger orgasms and reduced discomfort.
Psychological Factors: Addressing stress, anxiety, and relationship dynamics can have a profound impact on desire.
Let’s Talk About It—Your Sexual Health Matters
Many women hesitate to bring up sexual concerns, but your pleasure and well-being deserve attention. If you’re struggling with low libido and want to explore your options, we’re here to help.
At Vitality, we offer a private, judgment-free space to discuss your concerns and develop a personalized treatment plan. Whether it’s medication, hormone balancing, lifestyle adjustments, or all of the above, we’ll help you reclaim your confidence and sexual well-being.
Ready to Take the Next Step?
Book a confidential consultation today and let’s start the conversation. Because your sexual health is just as important as any other aspect of your well-being.
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